Investment ithandizira zomwe zikubwera za IGALMI ™ ku US komanso kupititsa patsogolo mapaipi azachipatala
NEW HAVEN, Conn., Epulo 19, 2022 (GLOBE NEWSWIRE) - BioXcel Therapeutics, Inc. (NASDAQ: BTAI) ("Company" kapena "BioXcel Therapeutics"), kampani yomwe imagwiritsa ntchito njira zanzeru zopanga kupanga Commerce-siteji biopharmaceutical kampani yosintha mankhwala mu neuroscience ndi immuno-oncology, lero yalengeza mgwirizano wandalama ndi Oaktree Capital Management, LP ("Oaktree") ndi ndalama zomwe zimayendetsedwa ndi Qatar Investment Authority ("QIA"). Pansi pa mgwirizano, Oaktree ndi QIA adzapereka ndalama zokwana $260 miliyoni zothandizira ntchito zamalonda za kampani ya IGALMI™ (dexmedetomidine) sublingual membrane.Kuonjezera apo, ndalamazo zikuthandizira kukulitsa ntchito zachitukuko zachipatala za BXCL501, kuphatikizapo pulogalamu yofunikira ya Phase 3 ya chithandizo chamankhwala. agitation mu Alzheimer's disease (AD) odwala, komanso kampani yowonjezera neuroscience ndi immuno-oncology Clinical project.
Njira yopezera ndalama kwanthawi yayitali imatsogozedwa ndi Oaktree ndipo imaphatikizapo izi:
Pansi pa mgwirizanowu, BioXcel Therapeutics ilandila chivomerezo kuchokera ku US Food and Drug Administration (FDA) kuti igwiritse ntchito mankhwala akampani a BXCL501 pochiza matenda a schizophrenia kapena bipolar I kapena II matenda akulu. Epulo 5, 2022, kutsatira kuvomerezedwa ndi FDA kwa IGALMI.
Zinthu zazikuluzikulu zandalamazo zikuphatikiza chiwongola dzanja chokhacho chokhala ndi zaka zisanu ndi chivomerezo cha FDA cha BXCL501 chothandizira kuthana ndi vuto la matenda a Alzheimer's. , kuphatikizapo BXCL701, oral innate immune activator wa kampaniyo. Mogwirizana ndi Income Interest Financing Agreement, Oaktree ndi QIA adzalandira malipiro a Income Interest Financing, malinga ndi chiwongoladzanja chobwezera, pa malonda onse a IGALMI ndi BXCL501 ina iliyonse yamtsogolo. Zogulitsa ku United States.Chiwongola dzanja chandalama chimachokera ku 0.375% mpaka 7.750% ya zogulitsa zapachaka za IGALMI ndi zina zilizonse zamtsogolo za BXCL501 ku US Kuwombola mapangano opangira chiwongola dzanja pazaka zitatu zoyambirira. Zimaphatikizansopo ndalama zokwana madola 5 miliyoni m'makampani wamba, posankha Oaktree ndi QIA, malinga ndi mgwirizano wangongole pamtengo pagawo lililonse lofanana ndi 10% yamtengo wapatali kuposa 30% yomwe ingayambitse Oaktree. ndi/kapena QIA kuti agwiritse ntchito njirayo Mtengo wapakati wolemedwa ndi voliyumu tsiku lililonse.
Kutsatiridwa kwa malondawa, komanso ndalama zomwe kampaniyo ikuyembekezeka kuchita komanso ndondomeko yabizinesi yomwe ikuyembekezeka, BioXcel Therapeutics ikuyembekeza kukhala ndi ndalama zogwirira ntchito zazaka zambiri.
"Kutsatira kuvomereza kwathu kwaposachedwa kwa IGALMI komanso kulengeza kwachuma kwamasiku ano, sitinakhalepo ndi mwayi wozindikira masomphenya athu oti ndikhale kampani yotsogola yaukadaulo yaukadaulo," adatero Dr. Vimal Mehta, CEO wa BioXcel Therapeutics."Ndife okondwa Kulimbitsa udindo wathu wandalama makamaka ndi ndalama zosachepera pomwe tikukonzekera kukhazikitsa IGALMI ndikupititsa patsogolo njira yathu yokulirapo ya zipilala zitatu za chilolezochi, zomwe zikuphatikiza kutsata zidziwitso zina, kukulitsa malo athu ndikukulitsa malo a IGALMI azachipatala. .Pakadali pano, tikudzipereka kupititsa patsogolo mbiri yathu ya neuroscience ndi immuno-oncology, kuphatikiza BXCL502 ndi BXCL701.
"Ndife okondwa kuyanjana ndi BioXcel Therapeutics munthawi yomwe ikubwerayi, makamaka kuvomerezedwa kwaposachedwa komanso kukhazikitsidwa kwa malonda kwa IGALMI ngati chithandizo chamankhwala chovuta kwambiri chokhudzana ndi schizophrenia wamkulu kapena bipolar I kapena II matenda," adatero Aman Kumar, Co. -Portfolio Manager wa Oaktree Life Sciences Lending. dziko.”
Zambiri zokhuza njira zopezera ndalama zafotokozedwa mu Fomu 8-K ya BioXcel Therapeutics ku US Securities and Exchange Commission (SEC).
IGALMI (dexmedetomidine) filimu yaing'ono, yomwe poyamba imadziwika kuti BXCL501, ndi filimu yapakamwa yosungunuka ya dexmedetomidine yosonyezedwa pofuna kuchiza odwala omwe ali ndi schizophrenia kapena bipolar disorder moyang'aniridwa ndi wothandizira zaumoyo. Chitetezo ndi mphamvu ya IGALMI sichinakhazikitsidwe kupitirira maola 24 pambuyo pa mlingo woyamba. , mayesero a gulu lofananira Phase 3 akuwunika IGALMI pa chithandizo chamankhwala Agitation kugwirizana ndi schizophrenia.SERENITY I) kapena bipolar I kapena II matenda (SERENITY II).
BioXcel Therapeutics, Inc. ndi kampani ya biopharmaceutical yomwe imagwiritsa ntchito njira zanzeru zopangira kupanga mankhwala osintha mu neuroscience ndi immuno-oncology. Njira yopangiranso mankhwala akampani imathandizira kugwiritsa ntchito mankhwala ovomerezeka omwe alipo kale komanso/kapena omwe adavomerezedwa ndichipatala komanso deta yayikulu ndi makina ogula. Kuphunzira ma aligorivimu kuti azindikire zizindikiro zochiritsira zatsopano.Zogulitsa zamakampani za IGALMI (zopangidwa ngati BXCL501) ndizopanga filimu ya dexmedetomidine ya sublingual yovomerezeka ndi FDA yochiza pachimake cha kusokonezeka kokhudzana ndi schizophrenia kapena bipolar I kapena II matenda mwa akulu .BXCL501 Kuwunikiridwa kwa chithandizo chachikulu cha matenda a Alzheimer's, komanso ngati chithandizo chothandizira matenda akulu akuvutika maganizo. Kampaniyo ikupanganso BXCL502, chithandizo chomwe chingathe kudwala matenda a dementia, ndi BXCL701, kufufuza, kuperekedwa pamlomo kwa innate immune activator. chithandizo cha khansa ya prostate yaukali ndi zotupa zolimba zolimba, zomwe ndi zoletsa kapena zosagwiritsidwa ntchito poyang'ana zoletsa.Kuti mudziwe zambiri, pitani www.bioxceltherapeutics.com.
BofA Securities adakhala ngati mlangizi yekha wa BioXcel Therapeutics ndipo Cooley LLP adakhala ngati mlangizi wa zamalamulo ku BioXcel Therapeutics.Sullivan & Cromwell LLP ndi phungu ku Oaktree ndi Shearman & Sterling LLP ndi phungu ku QIA.
Oaktree ndi kampani yotsogola kwambiri padziko lonse lapansi yoyang'anira ndalama zomwe zimagwira ntchito zina, zomwe zili ndi $ 166 biliyoni zomwe zikuyendetsedwa kuyambira pa Disembala 31, 2021. investing.assets and lists stocks.Kampaniyi ili ndi antchito ndi maofesi opitilira 1,000 m'mizinda 20 padziko lonse lapansi.Kuti mumve zambiri, pitani patsamba la Oaktree pa http://www.oaktreecapital.com/.
Qatar Investment Authority ("QIA") ndi thumba la chuma chodziyimira pawokha la State of Qatar.QIA idakhazikitsidwa mchaka cha 2005 kuti akhazikitse ndi kuyang'anira National Reserve Fund.QIA ndi imodzi mwachuma chachikulu komanso chogwira ntchito kwambiri padziko lonse lapansi. QIA imayika ndalama m'magulu osiyanasiyana a chuma ndi madera ndipo imagwira ntchito ndi mabungwe otsogola padziko lonse lapansi kuti apange mbiri yapadziko lonse lapansi yokhala ndi masomphenya anthawi yayitali kuti abweretse phindu lokhazikika ndikuthandizira ku chitukuko cha Qatar. Kuti mumve zambiri za QIA, chonde pitani patsamba lake www.qia.qa.
Kutulutsa kwa atolankhaniku kumaphatikizapo "zoyang'ana kutsogolo" mkati mwa tanthawuzo la Private Securities Litigation Reform Act ya 1995.Mawu omwe amayang'ana kutsogolo m'mawu atolankhani akuphatikiza, koma samangokhala: kukhazikitsidwa kwa malonda kwa IGALMI ku US kuchitira chipwirikiti mu odwala omwe ali ndi schizophrenia ndi bipolar disorder;ndondomeko zachitukuko zachipatala, kuphatikizapo chitukuko cha kampani cha BXCL501, chothandizira odwala omwe ali ndi vuto la maganizo Agitation komanso ngati chithandizo chothandizira matenda aakulu a maganizo;ndondomeko za kukula kwa kampani;ndalama zomwe zimayembekezeredwa motsatira mapangano ndi Oaktree ndi QIA komanso njira yoyendetsera ndalama zomwe kampaniyo ikuyembekezeka komanso kukwanira kwa chuma chamakampani. Akagwiritsidwa ntchito pano, mawu ophatikiza "kuyembekezera," "akufuna," "kukonzekera," "zotheka," "atha," “pitirizani,” “kufuna,” “kupanga,” “chandanda,” ndi mawu ena ofananawo amatanthauza Pozindikira ziganizo zoyang’ana kutsogolo.Kuonjezera apo, mawu aliwonse kapena chidziwitso, kuphatikizapo kuganiza mozama, zokhudzana ndi ziyembekezo, zikhulupiriro, mapulani, zoneneratu. , zolinga, ntchito kapena zizindikiro zina za zochitika zam'tsogolo kapena zochitika, zikuyang'ana kutsogolo.Nkhani zonse zoyang'ana kutsogolo zimachokera ku ziyembekezo zamakono za kampani ndi malingaliro osiyanasiyana.Kampani imakhulupirira kuti ziyembekezo ndi zikhulupiriro zake zili ndi zifukwa zomveka, koma ndizo. chibadwa chosatsimikizika.Kampaniyo sangakwaniritse ziyembekezo zake, ndipo zikhulupiriro zake sizingakhale zolondola.Zotsatira zenizeni zingakhale zosiyana kwambiri ndi zomwe zafotokozedwa kapena kufotokozedwa ndi ziganizo zoyang'ana kutsogolo monga zotsatira za zinthu zosiyanasiyana zofunika, kuphatikizapo, koma osangokhala: Kampani ikufuna ndalama zowonjezera komanso kuthekera kokweza ndalama ngati pakufunika;FDA ndi maulamuliro akunja ofanana Njira yovomerezeka yovomerezeka ndi yayitali, imatenga nthawi, yokwera mtengo komanso yosayembekezereka;kampaniyo ili ndi chidziwitso chochepa pakupeza mankhwala ndi chitukuko cha mankhwala;owongolera sangavomereze kapena kuvomerezana ndi malingaliro a kampani, kuyerekezera, kuwerengera, zomaliza kapena kusanthula, kapena mwina Kufunika kwa kutanthauzira kapena kuyeza deta m'njira zosiyanasiyana, zomwe zingakhudze mtengo wa pulogalamu inayake, kuvomereza kapena kugulitsa zinthu zina. wokonda malonda kapena malonda ndi kampani yonse;kampaniyo ilibe chidziwitso pakutsatsa ndi kugulitsa mankhwala ndipo ilibe chidziwitso ndi IGALMI kapena BXCL501 malonda ndi malonda;IGALMI kapena makampani ena omwe akufuna kupangidwa ndi kampani sangakhale ovomerezeka kwa asing'anga kapena azachipatala;Kampani siyitha kupeza chilolezo chotsatsa BXCL501 ku Europe kapena madera ena;Kampani ingafunike ndalama zochulukirapo kuti ipangitse ndikuyesa mayeso a Zachipatala okhudzana ndi omwe akufuna kupanga ndikuthandizira ntchito zawo;makampani ayenera kutsatira malamulo osiyanasiyana ogwiritsidwa ntchito;Kusintha kwa chisamaliro chaumoyo kungasokoneze kupambana kwa malonda m'tsogolomu. Izi ndi zina zofunika zikukambidwa pansi pa mutu wakuti "Zowopsa" mu Lipoti lake Lapachaka pa Fomu 10-K la chaka chomwe chinatha pa December 31, 2021, monga momwe izi zingawonekere nthawi ndi nthawi. m'mafayilo ake ena ndi Zosintha za SEC, zopezeka pa webusayiti ya SEC pa www.sec.gov.Zifukwa izi ndi zina zofunika zitha kupangitsa kuti zotsatira zenizeni zikhale zosiyana kwambiri ndi zomwe zikuwonetsedwa ndi zomwe zikuwonetsedwera m'nkhani ino. -ziganizo zoyang'ana zikuyimira kuyerekezera kwa oyang'anira kuyambira tsiku la kutulutsidwa kwa atolankhani.Ngakhale kuti kampaniyo ingasankhe kusinthiratu mawu oyembekezera mtsogolo panthawi ina mtsogolo, kupatula monga momwe lamulo limanenera, limakana udindo uliwonse wochita izi, zochitika zotsatila zimapangitsa kuti maganizo athu asinthe.Mawu amtsogolowa asatanthauze kuti akuyimira maganizo a kampani pa tsiku lililonse pambuyo pa tsiku la kutulutsidwa kwa atolankhani.
1 Ndalamazo zikuphatikizanso zilolezo zogulira magawo omwe ali mukampani komanso zikalata zogulira mayunitsi a kampaniyo LLC, monga tafotokozera mokwanira mu lipoti laposachedwa la Fomu 8-K loti liperekedwe pa Epulo 19, 2022.
Nthawi yotumiza: May-07-2022